Guide effects
Each bar is one sgRNA. A common zero line separates enrichment and depletion.
CRISPR GENE EXPLORER
Immune Pressure Screen
From perturbation to a closer look.
Explore the uploaded sgRNA screen by gene, experimental group and comparison.
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Descriptive screen effects. Positive = enrichment; negative = depletion. Effect sizes are not significance calls. Replicate pairing and experimental context await confirmation.
Replicate counts
One point per sample: mean normalized sgRNA count across the selected gene’s guides. Vertical scale is log2(count + 1). These points are not gene expression.
02 / COMPARE
Browse the whole panel
Select a dot or gene to inspect its guides.
Select a point to inspect a gene.
| Gene | Median guide effect | Guides | Enriched / depleted | Library / QC class |
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03 / QUALITY
Controls & sample coverage
| Guides | Median effect | Min / max |
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Sample counts, normalization and replicate correlation
04 / METHODS
Read the screen in context
Counts to effects
Control-guide normalization is documented in MAGeCK’s method reference ↗. This explorer computes descriptive effects only; it does not run MAGeCK or report RRA results.